Manchester United suffered their worst defeat in 92 years against Liverpool, losing 7-0 at their arch rivals' home ground.
United manager Erik ten Hag accused his players of unprofessionalism and was seething after a disastrous second-half performance from his team.
Liverpool's victory, in which they scored six times in the second half, boosted their chances of qualifying for the Champions League.
Mohamed Salah became Liverpool's top scorer in the PL with two goals, while Cody Gakpo and Darwin Núñez also scored twice each, and Roberto Firmino made it 7.
The result was Liverpool's biggest victory over their rivals, and led to a post-match dressing down from an embarrassed Hag.
Here are some of Manchester United's biggest defeats in the Premier League in the past decade for comparison:
Manchester City humiliated Manchester United with a 6-1 victory at Old Trafford in October 2011.
Tottenham Hotspur crushed Manchester United with a 6-1 win at Old Trafford in October 2020.
Liverpool dominated with a 5-0 victory over Manchester United at Old Trafford in October 2021.
Everton stunned Manchester United with a 4-0 victory at Goodison Park in April 2019.
Tottenham Hotspur convincingly defeated Manchester United 3-0 at White Hart Lane in April 2016.
Liverpool secured a crucial 4-2 win over Manchester United at Old Trafford in May 2021.
Manchester City emerged victorious with a 3-1 win over Manchester United at Old Trafford in January 2020.